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Patrick Bogdanowicz on Muck Rack

Patrick Bogdanowicz

France
As seen in: Nature
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Articles

Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging - Scientific Reports

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By Gautier Doat, Patrick Bogdanowicz, Paul Bensadoun, Maïté Noizet, Benoît Béganton, Armony Philippe, Sandrine Alvarez-Georges, Amélie Tourette, Sandrine Bessou-Touya, Jean-Marc Lemaitre
| Nature Verified
Abstract Intrinsic and extrinsic factors, including lifestyle and sun exposure, can contribute to cell senescence, which impairs skin homeostasis, that may in turn lead to skin aging. Senescent cells have a specific secretome, called the senescence-associated secretory phenotype (SASP) that includes MMPs, CXCLs and S100A8/9. Reducing the SASP with senotherapeutics is a promising strategy to reduce skin aging.
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