Patrick Collombat on Muck Rack

Patrick Collombat

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As seen in: MDPI, Cell Reports Medicine
INSERM: Director of Research - Directeur de Recherche (DR1) DiogenX: Co-founder and Scientific Advisor - Co-fondateur et Conseiller Scientifique
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Articles

RSPO1, a potent inducer of pancreatic β cell neogenesis

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By Serena Silvano, Tiziana Napolitano, Magali Plaisant, Anette Sousa-De-Veiga, Hugo Fofo, Chaïma Ayachi, Benoit Allegrini, Samah Rekima, Estelle Pichery, Jérôme Becam, Valentin Lepage, Caroline Treins, Laura Etasse, Julien Thévenet, Gianni Pasquetti, Julie Kerr-Conte, François Pattou, Paolo Botti, Arduino Arduini, Jacques Mizrahi, Benjamin Charles, Patrick Collombat
| Cell Reports Medicine Verified
Keywords Rspo1 Wnt/β-catenin signaling β cell replication endocrine pancreas islets of Langerhans diabetes Introduction The pancreas is an endoderm-derived digestive organ composed of an exocrine compartment and an endocrine portion. Within the exocrine compartment acinar cells produce, store, and secrete digestive enzymes. Scattered throughout the pancreas parenchyma, endocrine cells are organized in highly vascularized cell clusters termed islets of Langerhans.
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