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Patrick Melchior

As seen in: Wiley Online Library, Journal of Translational Medicine
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Articles by Patrick Melchior

Efficacy of Preoperative Chemotherapy in Patients With Nephroblastoma and Imaging Findings Suggestive of Preoperative Tumor Rupture

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By Marvin Mergen, Norbert Graf, Nils Welter, Patrick Melchior
| Wiley Online Library Verified
AV1 4 weeks actinomycin and vincristin GPOH German Society of Pediatric Oncology and Hematology preop-CT preoperative chemotherapy RFS relapse-free survival WT Wilms tumor 1 Introduction A suspected rupture of a Wilms tumor (WT) at diagnosis poses unique clinical challenges, as it may increase the risk of peritoneal spread, complicate staging and treatment decisions [1-4].
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PD-L1+ CD49f+ CD133+ Circulating tumor cells predict outcome of patients with vulvar or cervical cancer after radio- and chemoradiotherapy - Journal of Translational Medicine

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By Erich Franz, Selina Gies, Patrick Melchior, Istvan Molnar, István Gábor Molnár, Russalina Stroeder, Maike Pohlers, Moritz Schäfer, Laura Theobald, Martina Sester, Barbara Walch-Rückheim, Gregor Olmes, Tanja Tänzer, Erich Franz Solomayer
| Journal of Translational Medicine Verified
Peripheral blood samples were obtained from 40 patients with vulvar cancer and 115 patients with cervical cancer before and during different therapeutic approaches as well as samples from untreated female age-matched immunocompetent controls (HC) and used for monitoring of CTC subsets constitution. A subpopulation of n = 40 age-matched HC were used in experiments for detection of CTCs via immunofluorescence (IF), respectively. In flow cytometry analysis a total of n = 115 HC were analyzed.
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The impact of the route to diagnosis in nephroblastoma

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By Marvin Mergen, Nils Welter, Rhoikos Furtwängler, Patrick Melchior
| Wiley Online Library Verified
1 INTRODUCTION Although nephroblastoma or Wilms tumor (WT) is rare, it is the most common childhood kidney tumor and can even seldomly arise in extra-renal sites without any association to the kidney.1 For more than 50 years this tumor has been treated in prospective multicenter and randomized trials by the International Society of Pediatric Oncology (SIOP), the Childrens' Oncology Group (COG), and others.2, 3 Outcome has improved over time with a long-term survival of 90% today.4, 5 The...
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