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Paul Ruff

As seen in: Forbes, Nature, Frontiers, AVS Forum, Daily Maverick, The Architects' Journal, The RIBA Journal, The Catholic Spirit
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Articles

A generalizable cross-continent prediction of esophageal squamous cell carcinoma using the oral microbiome - Communications Medicine

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By Shahd ElNaggar, Wenlong Chen, Muhammed Khan, Christopher G. Mathew, Paul Ruff, Zhezhen Jin, Alfred I. Neugut, Anil K. Rustgi, Anne-Catrin Uhlemann, Tal Korem, Julian Abrams, Leanne M. Prodehl, Thomas K. Marumo
| Nature Verified
Abstract Esophageal squamous cell carcinoma (ESCC) has a poor prognosis and limited tools for early detection. Saliva is easily accessible and its microbiome composition can serve as a marker for upper gastrointestinal tract disease. This study aims to evaluate the potential of an oral microbiome signature for classifying ESCC.
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Could depoliticising housing be the key to lasting change?

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By Paul Ruff, Richard Waite Verified
| The Architects' Journal Verified
It’s time to remove housing from the election cycle and depoliticise the sector to have any meaningful impact on our housing crisis. And the next government has the golden ticket to do so. The scale of the crisis means we need a broader, more inclusive cross-partisan strategy where tangible long-term policies are implemented to outlast the election cycle and increase housing delivery.
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Causal association between constipation and risk of colorectal cancer: a bidirectional two-sample Mendelian randomization study

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By Paul Ruff, Ali Reza Safarpour, Zhen Li
| Frontiers
1 Introduction Colorectal cancer (CRC) stands as a global health concern, contributing significantly to morbidity and mortality rates worldwide (1, 2). The quest to identify modifiable risk factors for CRC is of paramount importance to develop effective preventive strategies (3, 4). Among the potential risk factors, constipation, characterized by infrequent bowel movements or difficulty passing stools, has garnered attention for its potential association with CRC risk (5, 6).
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