Paul Svitil Briant

On Nov. 17, the Food and Drug Administration released the final guidance for assessing the credibility of computational modeling and simulation (CM&S) in medical device submissions. The guidance provides a greater level of clarity for the medical device industry as CM&S plays a growing role in supporting the development and regulatory submissions of new products through in silico evaluation and in silico clinical trials.

Summary Background Hearing loss affects access to spoken language, which can affect cognition and development, and can negatively affect social wellbeing. We present updated estimates from the Global Burden of Disease (GBD) study on the prevalence of hearing loss in 2019, as well as the condition's associated disability. Methods We did systematic reviews of population-representative surveys on hearing loss prevalence from 1990 to 2019.

Before the arrival of COVID-19, just around the corner from some of the trendiest restaurants in downtown Philadelphia at a clinic at the Mazzoni Center, hundreds of people got screening and treatment for sexually transmitted diseases each week. People would stop by for condoms and the waiting room was often filled with 20 people or more. The pandemic changed everything. "We don't even have a waiting room anymore," said Eric Paulukonis, the health center's director of prevention services.