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A Lost Opportunity: Early Nephrolithiasis as a Missed Indicator of Primary Hyperparathyroidism Over Eight Years

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By Kwame Nkrumah, Solomon Gyabaah, Seth Kyei-Fram, Paulinus Domeh
| Wiley Online Library Verified
1 Introduction Primary hyperparathyroidism (PHPT) is marked by elevated calcium and inappropriately high parathyroid hormone (PTH) levels [1-3]. It is predominantly caused by a single adenoma (85%), with multiple adenomas or hyperplasia accounting for about 15% of cases collectively, and it is rarely due to parathyroid carcinoma [3]. It is a common endocrine disorder with a reported prevalence of 23 cases per 10,000 women and 8.5 cases per 10,000 men in the United States [4, 5].
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