Paushali Mukherjee

Malaria impacts India more than anywhere else in southeast Asia, but relief could be on the way if the early promise of vaccines in development is fulfilled. Malaria remains a deadly disease around the world, primarily affecting children below the age of five. In southeast Asia, India is bearing the brunt, accounting for 80 percent of the region's malaria burden.

A total of 128 male subjects were evaluated for the presence of detectable PvDBPII antibodies at the first screening visit. From the 110 PvDBPII antibody negative subjects, 71 were further screened at the second screening visit for haematological and biochemical laboratory parameters, and predefined inclusion and exclusion criteria, as per approved protocol. From 49 subjects who met the enrolment criteria, 36 subjects were randomized in a 3:1 scheme in 3 cohorts.