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Articles

Human rhinovirus 16 infection modifies the microRNA landscape during epithelial cell infection.

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By Aref Kyyaly, Jamil Jubrail, Pax Bosner, Victoria Cappleman
| biorxiv.org
Abstract Human rhinovirus is a major driver of disease exacerbations for patients with asthma and chronic obstructive pulmonary disease. Importantly, the virus can disrupt immune cell functioning leading to secondary bacterial infections in these patients. MicroRNAs are important regulators of gene expression and control viral pathogenesis and immune cell functions. However, the role of different miRNAs during rhinovirus infections remains poorly defined.
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