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Folding and modulation of the helical conformation of Glycophorin A by point mutations
Folding and modulation of the helical conformation of Glycophorin A by point mutations† Pei-Yin Lee,‡a Abhilash Sahoo ‡b and Silvina Matysiak *c Abstract Transmembrane helix folding and self-association play important roles in biological signaling and transportation pathways across biomembranes. With molecular simulations, studies to explore the structural biochemistry of this process have been limited to focusing on individual fragments of this process – either helix formation or dimerization.
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