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MiR-522-3p inhibits proliferation and activation by regulating the expression of SLC31A1 in T cells

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By Hao Wang, Jiang Wang, Hengxiao Lu, Peidao Sun
| link.springer.com
Abstract We investigated the role of miR-522-3p in thymoma-associated myasthenia gravis (TAMG), and the mechanism of action in T cells. The miR-522-3p expression in normal serum, non-thymoma MG patient serum and TAMG patient serum and tissues was detected by quantitative real-time PCR (qRT-PCR), respectively. We assessed miR-522-3p expression in Jurkat cells and human CD4+ T cells after activation by anti-CD3 and anti-CD28 using qRT-PCR.
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