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Articles by Peiling Chen
Lung Cancer Location Drives Lateralized Ventilation Loss and Adverse Outcome
Keywords Non-Small Cell Lung Cancer Ventilation Perfusion Scintigraphy Regional Lung ventilation Get full text access Log in, subscribe or purchase for full access. References: 1. Siegel, R.L. ∙ Giaquinto, A.N. ∙ Jemal, A. Cancer statistics, 2024 CA Cancer J Clin. 2024; 74(1):12-49 2. Bray, F. ... Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin. 2024; 74(3):229-263 3. Wasswa-Kintu, S. ...
Integrative fragmentomic and mutational signature profile of plasma cfDNA for early lung cancer detection
Abstract Detecting lung cancer effectively in the general population is essential for optimizing treatment outcomes and improving the 5-year survival rate. While low-dose computed tomography (LDCT) is the current standard, it has limitations in broader populations. We developed a blood-based multi-omics model using whole-genome cell-free DNA (cfDNA) features to distinguish lung cancer from non-cancer individuals.
Association of pre-existing conditions with major driver mutations and PD-L1 expression in NSCLC
Previous studies have highlighted the role of driver mutations and PD-L1 expression in non-small cell lung cancer (NSCLC), but the association of these genetic and immunological features with pre-existing conditions, such as blood types, family history of cancer and comorbid diseases, remains unclear.
Targeted Delivery of Quinoxaline-Based Semiconducting Polymers for Tumor Photothermal Therapy
RETURN TO ARTICLES ASAPPREVFunctional Nanostruc...Functional Nanostructured Materials (including low-D carbon)NEXT Peiling Chen Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, China , Xiaoying Wang Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640,...
Autophagy-inhibiting biomimetic nanodrugs enhance photothermal therapy and boost antitumor immunity
Autophagy-inhibiting biomimetic nanodrugs enhance photothermal therapy and boost antitumor immunity Peiying Huang, Yin Yin Zhu, Hao Zhong, Peiling Chen, Qunying Shi, Jiaoyu Chen, Jinmei Lai, Yingfeng Tu, Shuwen Liu and Lihan Liu Abstract The instinctive protective stress responses of tumor cells hamper the low-temperature photothermal therapy (LTPTT), resulting in tumor recurrence and metastasis.
A Versatile Nanoagent for Multimodal Imaging-Guided Photothermal Cancer Therapy and Anti-Inflammation
A Versatile Nanoagent for Multimodal Imaging-Guided Photothermal Cancer Therapy and Anti-Inflammation Photothermal therapy (PTT) has drawn great attentions for cancer therapy because of its minimally invasiveness and high spatiotemporal selectivity, which still encounters severe obstacles like heat-resistence, metastasis and recurrence. A key reason for the treatment failure is the high inflammatory tumor microenvironment caused by the hyperthermia.
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