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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
TNF/TNFR1 axis restrains inflammation-suppressive myeloid subclusters to drive acute pancreatitis
Abstract Acute pancreatitis (AP) is a pancreatic inflammatory disorder that can progress to fatal systemic inflammation and multiorgan failure. Although tumor necrosis factor (TNF) signaling is a key regulator of inflammation, its contribution to AP progression and its therapeutic potential remain incompletely understood. We induced AP in wild-type and Tnfr1–/– mice using caerulein, pancreatic duct ligation, or L-arginine.
Characterization of key odorants in three black tea cultivars using sensomics and molecular docking
Abstract High-quality black tea is globally prized for its characteristic aromas, notably “floral” and “sweet” notes. The tea cultivar serves as the genetic foundation for the development of these signature scents. Therefore, precise identification of key odorants across different aroma types is scientifically essential to guide the targeted breeding of superior aromatic tea cultivars.
Plasma metabolic profiling as a novel fingerprint for diagnosis of colorectal carcinogenesis and malignant progression
Abstract Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, and non-invasive diagnostic tools for early detection are urgently needed. This study aimed to characterize plasma metabolic profiles associated with colorectal carcinogenesis and malignant progression, and to evaluate their diagnostic value across the disease spectrum from precancerous lesions to advanced CRC.
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