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Peiyuan Shen on Muck Rack

Peiyuan Shen

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Articles

Lactylation-related prognostic signature characterized in pancreatic ductal adenocarcinoma through public scRNA-seq dataset and machine learning algorithms: the TOP2A-H3K18la-NQO1 axis orchestrates malignant progression

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By Haodong Tang, Li N Liu, Yusheng Du, Dan Liu, Siyuan Tan, Hongqin Ma, Ji Wang, Wenxing Zhao, Tonglei Xu, Peiyuan Shen, Aozhong Hu, Xiangxu Shi
| Nature Verified
Abstract Lactate promotes histone lactylation, which affects protein transcription and translation, thereby influencing tumour cell progression. However, the role of lactylation in pancreatic ductal adenocarcinoma (PDAC) remains underexplored and warrants further investigation. Single-cell RNA sequencing (scRNA-seq) data (GSE154778) underwent quality control, dimensionality reduction, and clustering.
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