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Petruta Gurban

As seen in: Wiley Online Library, MDPI
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Articles

Dominance of mutations in epigenetic regulators and a diversity of signaling alterations in blast‐phase BCR::ABL1‐negative myeloproliferative neoplasms

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By Petruta Gurban, Cristina Mambet, Pharmacy Bucharest Romania, Anca Botezatu
| Wiley Online Library Verified
To the Editor: BCR::ABL1-negative myeloproliferative neoplasms (MPNs) can evolve to secondary acute myeloid leukemia (sAML) or blast-phase (BP) MPN, a very severe condition with lack of effective therapy.1 Leukemic transformation (LT) of MPNs displays a variable incidence according to MPN phenotype: 9%–13% in primary myelofibrosis (PMF), 3%–7% in polycythemia vera (PV), and 1%–4% in essential thrombocythemia (ET).1 Here, we investigated the mutational landscape, copy number variations (CNVs),...
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IJMS | Free Full-Text | Assessment of Total Antioxidant Capacity, 8-Hydroxy-2′-Deoxy-Guanosine, the Genetic Landscape, and Their Associations in BCR::ABL-1-Negative Chronic and Blast Phase Myeloproliferative Neoplasms

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By Cristina Mambet, Ana Iulia Neagu, Coralia Bleotu, Petruta Gurban
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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