Pharmacogenomics Unit

Corresponding Author Ivan Bièche Pharmacogenomics Unit, Department of Genetics, Institut Curie, PSL Research University, Paris, France Faculty of Pharmaceutical and Biological Sciences, INSERM U1016, Université de Paris Cité, Paris, France Address for correspondence: I Bièche, Pharmacogenomics Unit, Department of Genetics, Institut Curie, PSL Research University, Paris, France. e-mail: ivan.bieche@curie.fr Search for more papers by this author

Increasing epidemiological and animal experimental data provide substantial support for the role of aryl hydrocarbon receptor (AhR) in mammary tumorigenesis. The effects of AhR have been clearly demonstrated in rodent models of breast carcinogenesis and in several established human breast cancer cell lines following exposure to AhR ligands or AhR overexpression. However, relatively little is known about the role of AhR in human breast cancers.