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Pharmahungary Group

As seen in: Frontiers, Biomed Central (BMC)
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Articles

Tirzepatide, a dual GIP/GLP1-receptor co-agonist preserves cardiac function and improves survival in angiotensin II-induced heart failure model in mice: comparison to liraglutide | Cardiovascular Diabetology | Full Text

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By MTA-SE Momentum Cardio-Oncology, Pharmahungary Group
| Biomed Central (BMC)
Methods All procedures were approved by the National Scientific Ethical Committee on Animal Experimentation and the Semmelweis University's Institutional Animal Care and Use Committee (H-1089 Budapest, Hungary) in accordance with NIH guidelines (National Research Council [2011], Guide for the Care and Use of Laboratory Animals: Eighth Edition) and permitted by the government of Food Chain Safety and Animal Health Directorate of the Government Office for Pest County (project identification...
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Correction: IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT): a small animal acute myocardial infarction randomized-controlled multicenter study on the effect of ischemic preconditioning | Basic Research in Cardiology

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By Metabolic Disorders Programme, Riga Stradinš, Pharmahungary Group, Cape Town
| link.springer.com
Correction: Basic Research in Cardiology (2025) 120:335–346 https://doi.org/10.1007/s00395-025-01102-3 In the original article co-authors Gábor B. Brenner, András Makkos, Tamás G. Gergely and Nabil V. Sayour were missing from the author group due to an administrative error on the authors’ part. The authors contributed significantly to the study by generating all data from R-site 1 (see Fig. 3 and Supplementary Fig. 2).
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Reduced circulating CD63+ extracellular vesicle levels associate with atherosclerosis in hypercholesterolaemic mice and humans - Cardiovascular Diabetology

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By Pharmahungary Group, Austrian Cluster
| Biomed Central (BMC)
TC, LDL-C and HDL-C levels were initially measured in mice at 11 weeks of age before treatments (Baseline condition), after 12 weeks of HFD (HFD condition), or after reaching 22 months of age on normal diet (old age condition). TC levels in PCSK9−/− mice were significantly lower than WT in all three conditions, whereas in LDLR−/− mice serum cholesterol levels were significantly increased at all three conditions (Fig. 1A).
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