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Philaiphon Jongruamklang on Muck Rack

Philaiphon Jongruamklang

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Articles

Platelets inhibit erythrocyte invasion by Plasmodium falciparum at physiological platelet:erythrocyte ratios

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By Johan Rebetz, Rick Kapur, Landsteiner Laboratory, Philaiphon Jongruamklang
| Wiley Online Library Verified
1 INTRODUCTION Erythrocytes are the primary host cells for replication of the malaria parasite Plasmodium falciparum and the parasite takes advantage of many cell membrane proteins and glycoproteins to adhere to and invade these cells.1 Severe anaemia is a common clinical consequence of malarial disease, especially among children, and is the primary indication for blood transfusion in sub‐saharan Africa.2 However, anaemia is not the only consequence, and an accompanying thrombocytopenia can...
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