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Articles by Philippe Bégin
Efficacy and Safety of Ligelizumab in Individuals With Confirmed Peanut Allergy
Conflicts of Interest Philippe Bégin reports institutional funding from Novartis, DBV Technologies, Regeneron, and Sanofi and personal fees (consultation and speaker services) from Pfizer, Bausch Health, Novartis, Sanofi, ALK and AstraZeneca. Motohiro Ebisawa has participated as an advisory board member and/or speaker for ARS Pharmaceuticals, Viatris, Sanofi and Novartis, outside the submitted work.
Respiratory Related Hospitalization in Children With Exposure to Meconium Aspiration or Staining
1 Introduction Meconium-stained amniotic fluid is present in 5% to 20% of deliveries at term [1], but the long-term outcomes of exposed neonates are not fully understood. Meconium staining occurs when fetal colonic content is released in amniotic fluid during the prenatal period, and is a risk factor for perinatal respiratory complications, including meconium aspiration syndrome [1].
Unveiling a suspected dupilumab‐induced neuropathy in pediatric eosinophilic esophagitis
Corresponding Author Hugo Gagnon Pediatric Gastroenterology, Hepatology and Nutrition, Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada Correspondence Hugo Gagnon, Pediatric Gastroenterology, Hepatology and Nutrition, Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Côte-Sainte-Catherine, Montreal, QC, Canada.
Skin‐centered strategies in food allergy prevention
It is reasonable to consider using emollients and treating atopic dermatitis as strategies to prevent food allergy, although evidence is currently lacking due to concerns about study methodologies.
The use of omalizumab in food allergy
Corresponding Author Aikaterini Anagnostou Department of Pediatrics, Section of Immunology Allergy and Retrovirology, Texas Children's Hospital, Houston, Texas, USA Section of Allergy Immunology & Retrovirology, Baylor College of Medicine, Houston, Texas, USA Correspondence Aikaterini Anagnostou, Department of Pediatrics, Section of Immunology Allergy and Retrovirology, Texas Children's Hospital, Feigin Center, 1102 Bates Avenue Suite 330, MSBCM320, Houston, TX 77030, USA.
Varying Doses of Epicutaneous Immunotherapy With Viaskin Milk vs Placebo in Children With Cow’s Milk Allergy: A Randomized Clinical Trial
Key Points Question Was a safe and efficacious dose of Viaskin milk identified in this phase 1/2 clinical trial? Findings In this randomized clinical trial, a statistically significant treatment response was observed in children who received 12 months of daily epicutaneous immunotherapy (EPIT) with Viaskin milk at a dose of 300 μg compared with placebo, with no adverse safety signal observed.
Never Too Late - Food Allergy Desensitization In The Adult Population
Oral Immunotherapy (OIT) in the adult food allergic population has been identified as an important gap of knowledge in clinical practice guidelines. We aimed to assess and characterize the success of OIT in our patients 18 years and older. To read this article in full you will need to make a payment Article info Copyright © 2022 Published by Elsevier Inc.
Multisystem inflammatory syndrome in adults: Comparison with other inflammatory conditions during the Covid-19 pandemic
2. Materials and methods 2.1 Population We analyzed a cohort of 22,251 adults admitted to hospital for MIS-A, Kawasaki disease, toxic shock syndrome, or other Covid-19 complications between April 1, 2006 and March 31, 2021 in Quebec, Canada.
Management of IgE‐mediated food allergy in the 21st century
REVIEW ARTICLE This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1111/cea.14241 Abstract The 21st century has seen the propulsion of research in the field of food allergy, which has driven real changes in the clinical approach.
Matched cohort study of hospitalization in children who have siblings with cancer
Original Article Nathalie Auger MD, MSc, Corresponding Author Nathalie Auger MD, MSc nathalie.auger@inspq.qc.ca orcid.org/0000-0002-2412-0459 University of Montreal Hospital Research Center, Montreal, Quebec, Canada National Institute of Public Health of Quebec, Montreal, Quebec, Canada Department of Social and Preventive Medicine, School of Public Health, University of Montreal, Montreal, Quebec, Canada Department of Epidemiology, Biostatistics, and Occupational Health, McGill University,...
Maternal autoimmune disease and risk of hospitalization for autoimmune disease, allergy, and cancer in offspring
ORIGINAL ARTICLE Xiaotian Zhao, Xiaotian Zhao Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada Institut national de santé publique du Québec, Montreal, Quebec, Canada Contribution: Formal analysis (equal), Software (equal), Visualization (equal), Writing - original draft (lead) Search for more papers by this author Philippe Bégin, Philippe Bégin Sainte-Justine Hospital Research Centre, Montreal, Quebec, Canada Contribution:...
Reduction in Peanut Reaction Severity During Oral Challenge After 12 Months of Epicutaneous Immunotherapy
LETTER Philippe Bégin, Corresponding Author philippe.begin.med@ssss.gouv.qc.ca CHU Sainte-Justine, Montreal, QC, Canada Corresponding author Philippe Bégin, CHU Sainte-Justine, 3175 Côte-Ste-Catherine, Montréal, Canada, H3T 1C5 Email: philippe.begin.med@ssss.gouv.qc.ca Search for more papers by this author J. Andrew Bird, University of Texas Southwestern Medical Center, Dallas, TX, USA Search for more papers by this author Jonathan M.
Economic considerations on the usage of biologics in the allergy clinic
REVIEW Thomas Poder Department of Management, Evaluation and Health Policy, School of Public Health, University of Montreal, Montreal, QC, Canada Research center of the Institut universitaire en santé mentale de Montréal, Montreal, QC, Canada Search for more papers by this author Philippe Bégin Corresponding Author E-mail address: philippe.begin@umontreal.ca https://orcid.org/0000-0002-9089-4604 Department of Pediatrics, CHU Sainte‐Justine, Montreal, QC, Canada Corresponding author: Philippe...
The value of oral immunotherapy
EDITORIAL Thomas G Poder Department of Management, Evaluation and Health Policy, School of Public Health, University of Montreal, Montreal, Quebec, Canada Research center of the Institut universitaire de santé mentale de Montréal, Montreal, Quebec, Canada Search for more papers by this author Philippe Bégin Corresponding Author E-mail address: philippe.begin@umontreal.ca https://orcid.org/0000-0002-9089-4604 Departement of Medicine, Université de Montréal, Montreal, Quebec, Canada Departement...
Early introduction without screening is a good deal, if caregivers will buy it
More than three years after the LEAP trial,1 the best way to implement early introduction (EI) of foods to infants at high‐risk of food allergy (FA) is still a matter of debate. Given the cost of screening and limited healthcare resources, the perfect balance between fair resources allocation and optimal patient care can be elusive. Currently in Allergy, two cost‐effectiveness studies comparing different approaches to promote EI of peanut2 or egg3 in infants at high risk of FA are published.
Effect of Epicutaneous Immunotherapy on Inducing Peanut Desensitization in Peanut-Allergic Children: Topline Peanut Epicutaneous Immunotherapy Efficacy and Safety (PEPITES) Randomized Clinical Trial Results - Journal of Allergy and Clinical Immunology
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Epicutaneous immunotherapy was shown in a multi-center Phase 2 trial to provide therapeutic benefit for children with peanut allergy. To access this article, please choose from the options below Purchase access to this article Claim Access If you are a current subscriber with Society Membership or an Account Number, claim your access now.
Food Allergy Research & Education
Some doctors and other health care providers may recommend tests that are not scientifically proven to be effective in diagnosing food allergies. The Guidelines for the Diagnosis and Management of Food Allergy in the United States, published by the National Institute of Allergy and Infectious Diseases (NIAID) specifically lists tests that are unproven and nonstandardized and are NOT RECOMMENDED for the diagnosis of food allergy, many of which are included in the list below.
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