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Pimpri Pune India

As seen in: Wiley Online Library, British Pharmacological Society
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Articles

Comment on ‘An open-label, single-arm, dose-escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults’

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By Sant Tukaram Nagar, Pimpri Pune India, van Dijkman SC
| British Pharmacological Society
To the Editor, van Dijkman and colleagues report an open-label, single-arm, dose-escalating concentration–QT study in 38 healthy adults receiving paroxetine 20- to 60-mg QD, concluding that paroxetine does not prolong QTc to any clinically meaningful extent at therapeutic doses.1 The pharmacokinetic–pharmacodynamic modelling is technically competent, and the design follows ICH E14/S7B (2022) provisions for omitting placebo when prior suspicion of QT prolongation is low.
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Comment on “Impact of Diet and Drugs on Fecal Lachnoclostridium Gene Marker (m3) in Noninvasive Diagnosis of Colorectal Neoplasia”

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By Sant Tukaram Nagar, Pimpri Pune India, Abhay Saraf
| Wiley Online Library Verified
No abstract is available for this article. Data Availability Statement No new data were created; all data discussed are included in this article. References 1, , , et al., “Impact of Diet and Drugs on Fecal Lachnoclostridium Gene Marker (m3) in Non-Invasive Diagnosis of Colorectal Neoplasia,” Journal of Gastroenterology and Hepatology 41 (2026): 1213–1222.
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Commentary on: “Dual‐task gait test provides limited additional value for fall prediction in care‐requiring older adults: A prospective study”

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By Rachana Mehta, Ranjana Sah, Pimpri Pune India
| Wiley Online Library Verified
Please review our Terms and Conditions of Use and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of Use Use the link below to share a full-text version of this article with your friends and colleagues. Learn more.
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