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Articles

International Journal For Multidisciplinary Research

|
By Syeda Kulsum, Ayesha Naz, Pittala Divya
| ijfmr.com
A simple, accurate, and precise reverse-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the estimation of Palbociclib in bulk and tablet dosage form. Chromatographic separation was achieved using a Waters HPLC system (Alliance 2695) equipped with a PDA detector and Symmetry ODS C18 column (4.6 mm × 150 mm, 5 µm). The mobile phase consisted of acetonitrile and methanol (60:40 % v/v) at a flow rate of 1.0 mL/min.
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