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Pol Alonso Pernas on Muck Rack

Pol Alonso Pernas

As seen in: BioRxiv
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Articles

Aging-associated decline of phosphatidylcholine synthesis is a malleable trigger of natural mitochondrial aging.

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By Tetiana Poliezhaieva, Pol Alonso Pernas, Lilia Espada, Melike Bayar
| BioRxiv
Abstract Mitochondrial dysfunction is a prominent hallmark of aging contributing to the functional decline of metabolic plasticity in late life. While genetic distortions of mitochondrial integrity elicit premature aging, the mechanisms leading to "natural" aging of mitochondria are less clear. Here we initially used proteomics, genetics and functional tests in wild type C.
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