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Pradipta Ranjan Rauta

As seen in: Nature, MDPI, Science Magazine, Texas Medical Center
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Articles

Pancreatic Tumor Microenvironmental Acidosis and Hypoxia Transform Gold Nanorods Into Cell-Penetrant Particles for Potent Radiosensitization

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By Pradipta Ranjan Rauta
| Texas Medical Center
Abstract Coating nanoparticles with stealth epilayers increases circulation time by evading opsonization, macrophage phagocytosis, and reticuloendothelial sequestration. However, this also reduces internalization by cancer cells upon reaching the tumor. We designed gold nanorods (GNRs) with an epilayer that retains stealth properties in circulation but transforms spontaneously in the acidotic tumor microenvironment to a cell-penetrating particle.
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Pancreatic Tumor Microenvironmental Acidosis and Hypoxia Transform Gold Nanorods Into Cell-Penetrant Particles for Potent Radiosensitization

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By Pradipta Ranjan Rauta, Yuri Mackeyev, Keith Sanders, Valeria Gonzalez
| Texas Medical Center
Home > UTHealth > McGovern Medical School > Journal Articles > 1662 Mice, Animals, Gold, Tumor Microenvironment, Lysine, Glutamic Acid, Nanotubes, Neoplasms, Acidosis, Hypoxia, Cell Line, Tumor DOWNLOADS Included in Endocrinology, Diabetes, and Metabolism Commons, Neurosurgery Commons, Oncology Commons COinS
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Pharmaceuticals | Free Full-Text | An Insight into Advances in Developing Nanotechnology Based Therapeutics, Drug Delivery, Diagnostics and Vaccines: Multidimensional Applications in Tuberculosis Disease Management

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By Hitesh Chopra, Yugal Kishore Mohanta, Pradipta Ranjan Rauta, Ramzan Ahmed
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Hitesh Chopra 1,†, Yugal Kishore Mohanta 2,*,†, Pradipta Ranjan Rauta 3, Ramzan Ahmed 2,4, Saurov Mahanta 5, Piyush Kumar Mishra 6, Paramjot Panda 3, Ali A. Rabaan 7,8,9, Ahmad A. Alshehri 10, Basim Othman 11, Mohammed Abdulrahman Alshahrani 10, Ali S.
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