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Prajkta Kallurkar on Muck Rack

Prajkta Kallurkar

As seen in: The American Journal of Human Genetics
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Articles

Transforming blood-derived episignatures into cell-type-agnostic classifiers: A shortcut to prenatal episignatures

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By Sarah Goodman, Zain Awamleh, Andrei L. Turinsky, Daria Grafodatskaya, Bianca E. Russell, Karen Chong, Jung Min Ko, Ebba Alkhunaizi, David Chitayat, Elena Greenfeld, Stephen Scherer, Elizabeth McCready, Rosanna Weksberg, Sanaa Choufani, Nikola Reko, Arteen Torabi-Marashi, Prajkta Kallurkar
| The American Journal of Human Genetics Verified
Results To achieve our goal, we sought to derive a disorder-specific episignature capable of both positive and negative classification across different cell types and to evaluate its clinical utility in prenatal tissues. We focused on T21 as a proof of concept for NDDs, whereby we have collected a large cohort with T21 samples and controls derived from postnatal and prenatal tissues.
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