Pranchal Shrivastava

3.1. Properties of PS-Chitosan Material before and after Laccase Immobilization For a comprehensive determination of the morphological and physicochemical properties of the electrospun PS-chitosan material before and after laccase immobilization, Fourier transform infrared spectroscopy (FTIR), confocal microscopy (CLSM), zeta potential measurement, and scanning electron microscopy (SEM) were applied (see Figure 1 ).

Abstract Cytochrome P450 (CYP) are heme-containing enzymes involved in the metabolism of drugs and endogenous compounds. Humans have 57 known CYPs, with >200 mutations linked to severe disorders, highlighting their role in disease etiology. To investigate their pathogenicity, we performed an in-depth computational study, comparing pathogenic mutations with non-pathogenic ones.