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Prasannakumar Deshpande on Muck Rack

Prasannakumar Deshpande

As seen in: Wiley Online Library, BioRxiv
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Articles

JNK regulates GABAAR expression at the cell surface via the receptor clustering protein GIT1 (ArfGAP1)

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By Prasannakumar Deshpande, Elina Nagaeva, Artemis Varidaki, Valentina Sino
| BioRxiv
Abstract GABA type A receptors (GABAARs) receive inhibitory neurotransmitter input and control excitatory/inhibitory balance in the nervous system. Loss of GABAergic function leads to maladaptive changes in circuit dynamics associated with neuropsychiatric disorders, yet the adaptive mechanisms used by cells to regulate GABAAR availability are poorly understood. Previously, we identified that the stress-sensing kinase JNK1 promotes anxiety-like behaviours in mice.
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Chondroitin Sulfate‐Coated Heteroduplex‐Molecular Spherical Nucleic Acids

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By Pasi Virta, Prasannakumar Deshpande, Ville Tähtinen, Toni Laine
| Wiley Online Library Verified
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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Expanding the Molecular and Clinical Phenotype of Patients With De Novo Variants in KIF5C: A Six Patient Case Series

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By Patrik Hollos, Sara Gracie, Prasannakumar Deshpande, Karl De Dios
| Wiley Online Library Verified
1 Introduction The kinesin superfamily of proteins (KIF) act as ATP-dependent molecular motors to facilitate intracellular transport along microtubules (Hirokawa et al. 2009), a process that is critical in brain development, functioning, plasticity, and survival (Hirokawa, Niwa, and Tanaka 2010). The KIF proteins regulate transport of cargo such as vesicles, organelles, protein complexes, mRNAs, and chromosomes along microtubules within axons, dendrites, and synapses (Willemsen et al. 2014).
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