Prasanth Manohar

Abstract Background: Galleria mellonella, an advantageous model organism, to investigate the therapeutic potential of bacteriophages. Employing the Galleria mellonella (waxworm) model, this study involved infecting the larvae with pathogenic Staphylococcus aureus, followed by combination treatment with staph phages; vB_Sau_Saa90 and vB_Sau_Saa165 at the concentrations of 107 and 109 PFU/mL and oxacillin, at 100 mg/kg.

1. Introduction Klebsiella pneumoniae is a Gram-negative opportunistic pathogen that causes urinary tract, wound and soft tissue infections, pneumonia, and even life-threatening sepsis (Kamruzzaman and Iredell, 2019; Mackow et al., 2019). Moreover, the recent increase of carbapenemase-producing strains of K.

Introduction Antimicrobial resistance is one of the most serious global public health threats. Wars are often associated with antibiotic resistance outbreaks, and, consequently, the conflict in Ukraine has significantly impacted the local and global spread of аntimicrobial resistance (1–3). Combat-related injuries often present complex and challenging medical scenarios that require rapid and comprehensive treatment to ensure the best possible outcomes.