Pratik Sinha on Muck Rack

Pratik Sinha

Ahmedabad, Kolkata
As seen in: Alt News, Medium, BBC, Nature, Thorax, Firstpost, JAMA (The Journal of the American Medical Association), The Hindu, EBioMedicine, EClinicalMedicine, The Lancet and
Engineer applying infrastructure thinking to journalism problems. Co-founder & Editor, @AltNews. Misinformation, hate speech, platform accountability in India.

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Articles

The host response in sepsis: can it be quantified?

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By Pratik Sinha
| The Lancet Verified
Get full text access Log in, subscribe or purchase for full access. References 1. Cajander, S ∙ Kox, M ∙ Scicluna, BP ∙ et al. Profiling the dysregulated immune response in sepsis: overcoming challenges to achieve the goal of precision medicine Lancet Respir Med. 2024; 12:305-322 2. Singer, M ∙ Deutschman, CS ∙ Seymour, CW ∙ et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JAMA. 2016; 315:801-810 3. Michels, EHA ∙ Dequin, P-F ∙ Butler, JM ∙ et al.
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Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality

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By Narges Alipanah-Lechner, Lucile Neyton, Pratik Sinha, Carolyn Leroux
| The Journal of Clinical Investigation
Clinical Research and Public HealthClinical ResearchInflammationPulmonology Open Access | 10.1172/JCI196290 Authorship note: NAL and LN contributed equally to this work and have been designated as co–first authors. Published in Volume 136, Issue 3 on February 2, 2026 J Clin Invest. 2026;136(3):e196290. https://doi.org/10.1172/JCI196290. © 2025 Alipanah-Lechner et al. This work is licensed under the Creative Commons Attribution 4.0 International License.
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Multivariate protein landscape of host response in hospitalised patients with suspected infection in the emergency department - Nature Communications

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By Pratik Sinha, Carlos Lopez-Espina, Gregory Watson, Akhil Bhargava, shah khan, Matthew Sims, Karthik Iyer, Neil Evans, Philip Verhoef, Niko Kurtzman, Falgun Gosai
| Nature Verified
Abstract Suspected infection requiring hospitalisation has highly heterogenous presentation. Yet, variances in host response and its implications are largely unknown. In this multicentre cohort of 3802 individual patients presenting to the Emergency Department (ED) with suspected infection requiring hospitalisation, we apply uniform manifold approximation and projections and K-means clustering to 29 plasma proteins to identify biologically discrete host response clusters.
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