Priyatha Premnath

Abstract : The recent COVID-19 pandemic has highlighted the inadequacies of existing diagnostic techniques and the need for rapid and accurate diagnostic systems. Although molecular tests such as RT-PCR are the gold standard, they cannot be employed as point-of-care testing systems. Hence, a rapid, noninvasive diagnostic technique such as Surface-enhanced Raman scattering (SERS) is a promising analytical technique for rapid molecular or viral diagnosis.

Abstract The extracellular bone resorbing lacuna of the osteoclast shares many characteristics with the degradative lysosome of antigen-presenting cells. γ-Interferon–inducible lysosomal thiol reductase (GILT) enhances antigen processing within lysosomes through direct reduction of antigen disulfides and maintenance of cysteine protease activity.

Loading metrics Open Access Peer-reviewed Research Article Priyatha Premnath , Leah Ferrie, Dante Louie, Steven Boyd, Roman Krawetz Priyatha Premnath, Leah Ferrie, Dante Louie, Steven Boyd, Roman Krawetz Published: April 10, 2019 https://doi.org/10.1371/journal.pone.0215018 Figures Abstract p21(WAF1/CIP1/SDI1) is a critical sentinel of the cell cycle that plays an important role in determining cell fate with respect to proliferation, differentiation and apoptosis.