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Ultrathin 2D Multivariate Hydrogen-Bonded Organic Framework Nanosheets for Fluorescent DNA Sensing
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adma74657-sup-0001-SuppMat.docx79.7 MB Supporting File 1: adma74657-sup-0001-SuppMat.docx.
Il Tibet a Firenze: due mostre di successo con i paesaggi maestosi nascosti sul “Tetto del mondo”
Una veduta di Lhasa (Foto Consolato Repubblica Popolare Cinese) Pubblichiamo l’articolo di Qi YIN, Console Generale della Repubblica Popolare Cinese a Firenze sull’interessante scambio culturale riguardante le due mostre fiorentine sul Tibet con i paesaggi naturali maestosi e i gruppi etnici capaci di fare in qualche decennio un percorso che avrebbe richiesto millenni.
TRIM37 interacts with TRIM28 to maintain primordial germ cell identity during migration
Abstract During primordial germ cell (PGC) specification, repression of somatic programs is essential for the establishment of germline identity. However, mechanisms that safeguard PGC fate thereafter remain unknown. Here, we identify the E3 ubiquitin ligase TRIM37 as a critical safeguard of PGC fate during migration. Trim37 deficiency causes severe PGC defects beginning at embryonic day 9.5 (E9.5) with complete PGC depletion by E12.5, and leads to an aberrant transition toward somatic cell states.
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