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Qianjiale Gu on Muck Rack

Qianjiale Gu

As seen in: Nature
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Articles

Triglyceride enhancs NSCLC metastasis via lipid β-oxidation by RhoA-driven cytoskeletal remodeling in ECM-constrained microenvironments

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By Yufan ling, Lu Hou, Tianqi Yang, Yiwen Fang, Wanshi Li, Hailong Pei, Leyuan Zhou, Yingchu Dai, Qianjiale Gu
| Nature Verified
Abstract Elevated serum triglycerides (TG) are associated with poor prognosis in non-small cell lung cancer (NSCLC), but the mechanisms underlying this association remain unclear. Elucidating the role of TG in NSCLC metastasis may reveal novel therapeutic targets. A retrospective analysis was performed in 77 NSCLC patients stratified by serum TG levels. Survival was assessed using Kaplan–Meier analysis, and metastasis rates were compared using chi-square tests.
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