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Qianlu Feng

As seen in: Nature, BioRxiv
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Articles

Seq-Scope-eXpanded: spatial omics beyond optical resolution - Nature Communications

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By Angelo Anacleto, Qianlu Feng, Chun-Seok Cho, Yongha Hwang, Yichen Si, Jer-En Hsu, Rosane M. Teles, Robert L. Modlin, Johann E. Gudjonsson, Myungjin Kim, Chang H Kim, Hee-Sun Han, Alex William Schrader
| Nature Verified
Abstract Sequencing-based spatial transcriptomics (sST) enables transcriptome-wide gene expression mapping but falls short of reaching the optical resolution (200–300 nm) of imaging-based methods. Here, we present Seq-Scope-X (Seq-Scope-eXpanded), which empowers submicrometer-resolution Seq-Scope with tissue expansion to surpass this limitation.
Open in Who Shared Issue with article?

Social evolution and absence of olfactory function in larval honey bees

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By Tianfei Peng, Zhenqing Chen, Amy Ahmed, Qianlu Feng
| BioRxiv
Abstract Social evolution made larval honey bees dependent on adult colony members for feeding. We therefore predicted they have diminished olfactory capabilities, and based on organismal resource conservation theory, also have downregulated olfactory receptor (OR) gene expression. Behavioral assays demonstrated that larvae cannot find food via olfaction and expressed very low levels of Orco, an essential gene for OR function.
Open in Who Shared Issue with article?

Seq-Scope-eXpanded: Spatial Omics Beyond Optical Resolution

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By Weiqiu Cheng, Chun-Seok Cho, Angelo Anacleto, Qianlu Feng
| BioRxiv
Abstract Sequencing-based spatial transcriptomics (sST) enables transcriptome-wide gene expression mapping but falls short of reaching the optical resolution (200-300 nm) of imaging-based methods. Here, we present Seq-Scope-X (Seq-Scope-eXpanded), which empowers submicrometer-resolution Seq-Scope with tissue expansion to surpass this limitation.
Open in Who Shared Issue with article?
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