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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Multi-omic analysis of androgen-deprived human testes reveals Sertoli cell regulation and niche reprogramming
Abstract Testis development and male fertility depend on androgens, yet the mechanisms underlying their regulation of adult human testicular function remain poorly defined due to ethical and technical constraints. To address this, we leverage androgen-deprived adult human testes as a spontaneous model and construct a comprehensive multi-omics atlas integrating single-nucleus RNA sequencing, single-cell ATAC-seq, and spatial transcriptomics.
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