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Qianying Hu on Muck Rack

Qianying Hu

As seen in: Nature, MDPI, ACS Publications, Science Magazine, Physical Review B
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Articles

HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling

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By Qianying Hu, Qian Sun, Weifang Xiang, Zilong Zhou, Hongyan Sun, Yue Hu, Liehao Yang, Chenyu Wang, Fangqing Zhang, Yu Zhang, Yichuan Xiao, Xianling Cong, Yujia Cong
| Nature Verified
Abstract Hutchinson‑Gilford progeria syndrome (HGPS) is a rare premature aging disorder caused by mutations in the LMNA gene. High mobility group A1 (HMGA1) exhibits differential expression patterns across aging models. However, its roles and mechanisms in aging remain unclear.
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Ameliorating calcium homeostasis improves longevity and healthspan in progeroid and naturally aged mice

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By Weifang Xiang, Qianying Hu, Pingli Sun, Xiaohan Wu, Hui Jiang, Min Qu, Yu Wang, Zhiyao Wang, Xuan Liu, Jun Ma, DaHai Zhu, Hu Li, Yuanyi Wang, Yang Jiao, Baiqu Huang, Jun Lu, Xianling Cong, Wei Li, Yu Zhang
| Nature Verified
Abstract Cellular calcium (Ca2+)-regulating systems are compromised during aging-related disorders. Here, we show that disruption of Ca2+ homeostasis leads to the cytoplasmic accumulation of Ca2+ binding protein S100A6, which promotes Hutchinson-Gilford progeria syndrome (HGPS) and natural aging.
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Coupled exciton internal and center-of-mass motions in two-dimensional semiconductors by a periodic electrostatic potential

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By Fujia Lu, Qianying Hu, Yang Xu
| Physical Review B
We theoretically investigate the coupling between the exciton internal and center-of-mass motions in monolayer transition-metal dichalcogenides subjected to a periodic electrostatic potential. The coupling leads to the emergence of multiple absorption peaks in the exciton spectrum, which are the hybridizations of 1s, 2s, and 2p± Rydberg states with different center-of-mass momentums.
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