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Qiaohui Ying on Muck Rack

Qiaohui Ying

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Articles

Causal landscape of the circulating proteome in systemic iron overload revealed by Mendelian randomization and experimental validation

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By Mingwei Wang, Xia Lou, Qing Li, Chuang Li, Shuchang Dai, Xiaolin Du, Jue Wang, Zhong Liu, Qiaohui Ying
| Nature Verified
Abstract Systemic iron overload precipitates progressive and often irreversible organ dysfunction, yet the clinical toolkit for non-invasive, organ-specific monitoring of iron accumulation remains inadequate. This study leverages a proteome-wide causal inference framework to identify circulating biomarkers that drive or reflect iron deposition in the liver, spleen, and pancreas.
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