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Cascade Reactions of Aryl‐Substituted Terminal Alkynes Involving in Situ‐Generated α‐Imino Gold Carbenes
Introduction The indole moiety is a key structural component of many natural products, which exhibits privileged pharmacological and biological activities.1 Among them, 2-substituted indoles belong to one of the most prominent motifs of medicinally active compounds,1d, 2 for instance for ASIC3 inhibition or Rucaparib PARP inhibitor, etc. Aryl-annulated carbazoles are also attractive targets that show potential as highly promising antitumor3 and antibacterial4 agents.
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