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Qing-Ying Wang

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Articles

Insulin safeguards apoptotic fate of mesenchymal stem cells to sustain long-term therapeutic efficacy in type 2 diabetes

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By Zi-Qi Zhang, Chen-Xi Zheng, Hua Tian, Jing Ma, Zhe Li, Zhen Gong, Yu Fu, Bing-Dong Sui, Sha Zhang, Cheng-Biao Hu, Ying-Feng Gao, Qing-Ying Wang, Guang-Xiang He, Jiong-Yi Tian, Cheng-Yu Fang, Dong-Min Li
| Nature Verified
Abstract Type 2 diabetes mellitus (T2DM) remains a major global health challenge, and although mesenchymal stem cell (MSC)-based therapy has shown promise in targeting its core pathological features, its translational potential is limited by unstable efficacy, including limited therapeutic durability and marked variability associated with baseline insulin secretion and β-cell reserve.
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