Inflammation and metabolic disorders. Nature. 2006; 444: 860-867https://doi.org/10.1038/nature05485 Macrophages, inflammation, and insulin resistance. Annu. Rev. Physiol. 2010; 72: 219-246https://doi.org/10.1146/annurev-physiol-021909-135846 Weisberg S.P. McCann D. Desai M. Rosenbaum M. Leibel R.L. Ferrante A.W. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 2003; 112: 1796-1808https://doi.org/10.1172/JCI19246 Xu H.Y. Barnes G.T. Yang Q. Tan G.