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Qingying Chen

As seen in: Nature, Wiley Online Library, Microbiology Research
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Articles

PATTY corrects open-chromatin bias for improved bulk and single-cell CUT&Tag profiling

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By Shengen Hu, Zhangli Su, Lin Liu, Qingying Chen, Megan C. Grieco, Mengxue Tian, Anindya Dutta, Chongzhi Zang
| Nature Verified
Abstract Accurate epigenomic profiling is essential for understanding chromatin and gene regulation. Cleavage Under Targets & Tagmentation (CUT&Tag) enables efficient epigenomic profiling for low-input and single-cell samples and is increasingly adopted in genomics research. However, CUT&Tag’s usage of Tn5 transposase introduces bias toward open chromatin that distorts genome-wide signal patterns and confounds downstream analysis, especially in sparse single-cell data.
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Search Results

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By Songzhen Yang, Jiali Li, Xiang Rong, Qingying Chen
| Microbiology Research
Purpose. This study aims to investigate the synergistic antimicrobial activity of four phytoalexins in combination with fluoroquinolones against Ureaplasma spp., a genus of cell wall-free bacteria that are intrinsically resistant to many available antibiotics, making treatment inherently difficult. Methodology. A total of 22 958 urogenital tract specimens were assessed for Ureaplasma spp. identification and antimicrobial susceptibility.
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Curtobacterium phyllosphaerae sp. nov. and Curtobacterium guangdongense sp. nov., isolated from the citrus phyllosphere

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By Jiali Li, Xiang Rong, Qingying Chen, Songzhen Yang
| Microbiology Research
Volume 75, Issue 8 Article metrics loading... /content/journal/ijsem/10.1099/ijsem.0.006870 References Yamada K, Komagata K. Taxonomic studies on coryneform bacteria. V. Classification of coryneform bacteria. J Gen Appl Microbiol 1972; 18:417–431 [View Article] [Google Scholar] Parte AC, Sardà Carbasse J, Meier-Kolthoff JP, Reimer LC, Göker M. List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ.
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