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F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling
1 Introduction Gastric cancer remains one of the leading causes of cancer-related morbidity and mortality worldwide. Despite significant advances in surgery, chemoradiotherapy, targeted therapy, and immunotherapy, survival outcomes for patients with advanced gastric cancer remain poor [1, 2]. Metastasis is the major contributor to poor outcomes in gastric cancer, and tumor immune evasion promotes disease progression and limits the efficacy of immunotherapy [3-5].
Prospective clinical evidence from over 1,000 pan-cancer patients: a complement to fosaprepitant in the prevention of chemotherapy-induced nausea and vomiting | BMC Cancer | Full Text
This study applied a prospective, observational (non-randomized) design, recruiting patients receiving anticancer agents from March 2021 to August 2021. This work didn’t interfere with clinical decision-making or risk beyond conventional treatment, enrolling and following only patients prescribed fosaprepitant. No identifiable information will be included in the recorded data to protect the privacy of the subjects.
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