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Qiuying Nie

As seen in: Wiley Online Library
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Articles

The Role of Protein Disulfide Isomerase Inhibitors in Cancer Therapy

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By Junwei Yang, Junmin Zhang, Qiuying Nie, Xiedong Zhou
| Wiley Online Library Verified
Protein disulfide isomerase (PDI) is a member of the mercaptan isomerase family, primarily located in the endoplasmic reticulum (ER). At least 21 PDI family members have been identified. PDI plays a key role in protein folding, correcting misfolded proteins, and catalyzing disulfide bond formation, rearrangement, and breaking. It also acts as a molecular chaperone.
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Pristimerin inhibits thioredoxin reductase in the treatment of non-small cell lung cancer

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By Xiedong Zhou, Qiuying Nie, Yajun Chu, Qianhe Xu
| scienceopen.com
Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce; Supuran CT. Natural Products in Drug Discovery: Advances and Opportunities. Nature Reviews Drug Discovery. 2021. Vol. 20:200–216 Harvey AL, Edrada-Ebel R, Quinn RJ. The Re-Emergence of Natural Products for Drug Discovery in the Genomics Era. Nature Reviews Drug Discovery. 2015. Vol. 14:111–129 Mullowney MW, Duncan KR, Elsayed SS, Garg N, van der Hooft JJJ, Martin NI, et al..
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