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Qiying Lu on Muck Rack

Qiying Lu

As seen in: Nature
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Articles

Sympathetic nervous system-mediated fibro-adipogenic progenitor mobilization drives stroke-related sarcopenia

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By Yinong Huang, Yilin Liu, Ruijie Li, Mingming Fan, Yixuan Liu, Yiling Wang, Xin Sui, Xiaofeng Yuan, Qiying Lu, Yuan Qiu, Ruijun Li, Jierui Chen, Bingjun Zhang, Sanxin Liu, Yuanchen Ma, Xiaofan Lai, Jie Ren, Zhengqi Lu, Huimin Yi, Weijun Huang, Jiancheng Wang, Yanbing Li, Haipeng Xiao, Andy Xiang, Chuyun Ou
| Nature Verified
Abstract Patients who survive stroke usually experience rapid muscle wasting and an increased risk of physical disability. Although multifactorial interactions, including malnutrition, disuse, systemic catabolic imbalance, and neurohormonal dysregulation, are thought to contribute to the progression of stroke-related sarcopenia, the underlying mechanisms of this brain–muscle crosstalk remain elusive.
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An extracellular vesicle-mediated mitochondrial transfer network critical for testosterone synthesis - Nature Cell Biology

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By Kai Xia, Suyuan Zhang, Hao Peng, Hainan Chen, Jiajie Yu, Peng Luo, Hong Chang Chen, Li Huang, Yifei Xiong, Lei Jia, Lu Li, Yuan Qiu, Yan Guo, Hang Fan, Guihua Liu, Qiong Ke, TAO WANG, Weiqiang Li, Lili Chen, Chunhua Deng, Haipeng Xiao, Andy Xiang, Cuifeng Yang, Qiying Lu, Lerong Zhao, Congyuan Liu, Ziran Dai
| Nature Verified
Abstract Testosterone production by testicular Leydig cells (LCs) in male mammals is energetically demanding and prone to mitochondrial damage. Despite these challenges, LCs exhibit remarkable longevity and minimal turnover, suggesting the existence of specialized mechanisms that maintain LC mitochondrial homeostasis under such constrains. Here we identify a mitochondrial transfer network between LCs and different testicular macrophage (tMac) subpopulations.
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