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Quamarul Hassan on Muck Rack

Quamarul Hassan

As seen in: BioRxiv
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Articles

A bifunctional imprinted lncRNA scaffolds NuRD-HDAC1 to couple cis-activation of Dio3 with trans-repression of the osteoblast chromatin landscape

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By Quamarul Hassan, Yuechuan Chen, Benjamin J Wldman
| BioRxiv
Abstract Long non-coding RNAs (lncRNAs) frequently act at imprinted loci, yet how a single lncRNA can simultaneously activate its neighbor and repress distant genes through a shared chromatin platform remains poorly defined. We show that imprinted Dio3os performs this bifunctional role by scaffolding the nucleosome remodeling and histone deacetylase (NuRD-HDAC1) complex.
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K-homology Type Splicing Regulatory Protein: Mechanism of Action in Cancer and Immune Disorders

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By Quamarul Hassan
| dl.begellhouse.com
Volume 34, Issue 1, 2024, DOI: 10.1615/CritRevEukaryotGeneExpr.2023048085 Get access Quamarul Hassan University of Alabama ABSTRACT K homology-type splicing regulatory protein (KSRP) is emerging as a key player in cancer biology, and immunology. As a single-strand nucleic acid binding protein it functions in both transcriptional and post-transcriptional regulation, while facilitating multiple stages of RNA metabolism to affect proliferation and control cell fate.
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K-homology Type Splicing Regulatory Protein: Mechanism of Action in Cancer and Immune Disorders

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By Nabiha Yusuf, Jonathan Leavenworth, Quamarul Hassan
| dl.begellhouse.com
K-homology Type Splicing Regulatory Protein: Mechanism of Action in Cancer and Immune Disorders , DOI: 10.1615/CritRevEukaryotGeneExpr.2023048085 Get access Quamarul Hassan University of Alabama Jonathan Leavenworth Chromatin and RNA Biology Laboratory, Oral and Maxillofacial Surgery, Institute of Oral Health Research, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL, USA Nabiha Yusuf Department of Dermatology University of Alabama at Birmingham 1670 University...
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