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Quanlv Xu on Muck Rack

Quanlv Xu

As seen in: Frontiers
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Articles

A Case Report: Retroperitoneal dedifferentiated liposarcoma with heterologous myogenic differentiation and testicular metastasis

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By Runlin Feng, Yiqing Li, Changxing Ke, Haosong Ma, Guorun Zi, Quanlv Xu
| Frontiers
Abstract Dedifferentiated liposarcoma (DDLPS) is the most common retroperitoneal soft tissue sarcoma, characterized by MDM2 and CDK4 gene co-amplification. However, DDLPS with heterologous myogenic differentiation is extremely rare and poses a significant diagnostic challenge due to its expression of myogenic markers such as desmin, myogenin, and MyoD1, which can easily lead to misclassification as primary rhabdomyosarcoma.
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