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Quanying Zhang

As seen in: Wiley Online Library, Frontiers
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Articles

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Oral TYK2 Inhibitor D‐2570 in Healthy Subjects: A First‐in‐Human Phase I Study

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By Meng Wang, Quanying Zhang, Zhe Shi, Ling Zhang
| Wiley Online Library Verified
1 Introduction Janus kinases (JAKs), including JAK1, JAK2, JAK3, and tyrosine kinase 2 (TYK2), are a family of intracellular tyrosine kinases that are involved in the signaling process of many cytokine receptors. The inhibition of JAKs is considered an important modulator of the JAK–STAT (signal transduction and activator of transcription) signaling pathway in immune-mediated diseases including rheumatoid arthritis, psoriasis, systemic lupus erythematosus, and inflammatory bowel disease [1, 2].
Open in Who Shared Issue with article?

Postoperative kinesiophobia in elderly patients with femoral neck fractures: a prospective study of psychological and social determinants

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By Ling Zhou, Min Zhang, Xiaofang Hu, Jialu Hou, Jie Cheng, Xia Shen, Kankai Guo, Qiaoqian Wang, Quanying Zhang
| Frontiers
ORIGINAL RESEARCH article Volume 16 - 2025 | https://doi.org/10.3389/fpsyg.2025.1622585 Highlights • This study provides the first comprehensive analysis of multiple influencing factors of postoperative kinesiophobia in elderly patients with femoral neck fractures. • This study finds that a low education level is a significant risk factor for kinesiophobia. • This study reveals that social support and psychological resilience are negatively correlated with kinesiophobia.
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