Quentiin Delaunay on Muck Rack

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Articles

Collective directional memory controls the range of epithelial cell migration

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By Helena Canever, Hugo Lachuer, François Sipieter, Quentiin Delaunay
| biorxiv.org
Abstract Cell migration is a fundamental behavior involved in multicellular development, tissue regeneration and homeostasis, which is deregulated in cancer. Epithelial cells migrate individually when isolated and collectively in a tissue, and may be exposed to external guidance cues. How interactions between neighbors affect the efficiency of cell spatial exploration - the distance cells can reach in a given time - and sensitivity to external guidance cues is, however, poorly understood.
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