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Quenton Hurst

As seen in: BioRxiv
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Articles

A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system

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By Mark Reglinski, David Williams, Marek Gierlinski, Quenton Hurst
| BioRxiv
Abstract The ability to compete with diverse competitors is essential for bacteria to succeed in microbial communities. A widespread strategy for inter-bacterial competition is the delivery of antibacterial toxins, or effector proteins, directly into rival cells using the Type VI secretion system (T6SS). Whilst a large number of broad-spectrum enzymatic T6SS effectors have been described, relatively few which form pores in target cell membranes have been reported.
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