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Quia C. Claybourne

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Articles

Reducing HuD Levels Alleviates Alzheimer's Disease Pathology in 5xFAD Mice

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By Eunbyul Ji, Apala Pal, Marc Michel, Quia C. Claybourne
| Wiley Online Library Verified
AD Alzheimer's disease APP amyloid precursor protein Aβ amyloid-beta cKO conditional knockout Elavl4 embryonic lethal abnormal vision-like 4 gDNA genomic DNA IHC immunohistochemistry 1 Introduction Alzheimer's disease (AD) is the most common neurodegenerative disorder and its main risk factor is age (Querfurth and LaFerla 2010; Guerreiro and Bras 2015). A major hallmark of AD pathology is the accumulation of amyloid beta (Aβ) plaques (Chen et al.
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