Qurat ulain on Muck Rack

Qurat ulain

As seen in: Nature

Get in touch with Qurat

Contact Qurat, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Articles

Prognostic significance of IDH1 promoter methylation and associated genome-wide alterations in breast cancer

|
By Summayya Anwar, Azam Khan, Sadia Yasmin, Qurat ulain, Erum Najeeb, Muhammad A. Saeed, Alfar Ahmad, Mirza Imran Shahzad
| Nature Verified
Abstract Dysregulation of IDH1, a key metabolic enzyme, is widely reported across cancers and affects both tumor biology and patient prognosis. However, its regulation and associated epigenetic alterations in breast cancer (BC) remain unclear. This study examined methylation of two CpG islands (I1, I2) within the IDH1 promoter and a putative distal enhancer in clinical BC samples, correlating these patterns with IDH1 expression and clinicopathological features.
Open in Who Shared Issue with article?
See all 1 articles
 •  Privacy  •  Terms  •  Security and Legal  •   •   •   • 

© 2026 Muck Rack

SOC 2® Certified