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Rachel Matrenec on Muck Rack

Rachel Matrenec

As seen in: BioRxiv
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Articles

The Epithelial-to-Mesenchymal Transition Supports HCMV Infection and Biosynthesis in Mammary Epithelial Cells Through Two Distinct Mechanisms.

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By Preethi Golconda, Mariana Andrade-Medina, Rachel Matrenec, Alan McLachlan
| BioRxiv
Abstract Human cytomegalovirus (HCMV) infects a wide range of cell types in the body, including a variety of epithelial cell types. Despite the significance of epithelial cells during infection, HCMV has been difficult to study in epithelial cells. In this study, we examined HCMV infection in mammary and prostate epithelial cell lines, finding that the virus establishes a semi-permissive, biosynthetically abortive state.
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Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy

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By Xing Liu, Michaela U. Gack, Rachel Matrenec
| asm.org
Virus-Cell Interactions Xing Liu, Rachel Matrenec, Michaela U. Gack, Bin He Richard M. Longnecker, Editor DOI: 10.1128/JVI.00497-19 ABSTRACT The Us11 protein encoded by herpes simplex virus 1 (HSV-1) functions to impair autophagy; however, the molecular mechanisms of this inhibition remain to be fully established.
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