Rachelly Normand

Abstract Thyroid hormone, produced in the thyroid gland, regulates metabolism, development, and cardiac function. The thyroid is susceptible to autoimmune attack by both cellular and humoral immunity, exemplified by Hashimoto's thyroiditis (HT) and Graves disease (GD), respectively. In HT, immune-mediated destruction impairs thyroid hormone production, while in GD, stimulating autoantibodies promote over-production.

A-C.V. has a financial interest in 10X Genomics. The company designs and manufactures gene sequencing technology for use in research, and such technology is being used in this research. A-C.V.'s interests were reviewed by The Massachusetts General Hospital and Mass General Brigham in accordance with their institutional policies. J.R.H. consults for CJ CheilJedang and Interon Laboratories. A.G.E. consults for Mirvie, Inc.

This webinar is brought to you by the Science/AAAS Custom Publishing Office. 8 Sep 2021 12:00 PM ET Register NOWRemaining time: Rachelly Normand, Ph.D.Speaker Jackie Oberst, Ph.D.Moderator SARS-CoV-2 infection may cause acute respiratory disease and, in some patients, result in multiorgan failure. In-depth understanding of its disease pathophysiology and the underlying reasons for interpatient symptom variability are still lacking.